Jane Allen Consulting, Inc.

Regulatory Toxicology and Technical Management Services

 


Publications and Abstracts

From 1990 to present:

1. Allen, JS et al. Testing of clofibrate, benzene, 12-o-tetradecanoyl phorbol-13-acetate, dimethyl vinyl chloride, p-cresidine, and cyclophosphamide in micronucleus assays in p53+/-, p53+/+, Tg.AC hemizygous, and FVB mice. Toxicological Pathology 29S: 307-308 (2001).

2. Torrey CE, Allen JS, Miller RT, Wall HG, Selinger K and Rickert DE. Testing of clofibrate in a 6-month gavage study using Tg.AC hemizygous mice. Toxicological Pathology 29S: 304-305.

3. Torrey CE, Allen JS, Wall HG, Selinger K, and Rickert DE. Testing of clofibrate in a 6-month dermal administration study using Tg.AC hemizygous mice. Toxicological Pathology 29S: 288-290 (2001).

4. Nesfield SN, Allen JS, Klapwyk JC, Clarke CJ, Selinger K, and Rickert DE. Testing of clofibrate in a six-month gavage study using RasH2 mice. Toxicological Pathology 29S: 241-243 (2001).

5. Torrey, CE, Allen JS, Selinger K, Mann P, Miller RT and Rickert DE. Testing of clofibrate in a 6-month gavage study using p53+/- mice. Toxicological Pathology 29S: 205-207 (2001).

6. Nesfield SN, Allen JS, Williams TC, Selinger K, and Rickert DE. Testing of clofibrate in a one-year neonatal CD-1 mouse assay. Toxicological Pathology 29S: 201-202 (2001).

7. ILSI Alternatives to Carcinogenicity Testing Compound Coordinators. Rationale statements for selection of compounds to be tested in ILSI alternatives to Carcinogenicity Testing program. Toxicological Pathology 29S: 323-328 (2001).

8. Intravenous toxicity of dimethylsulfoxide (DMSO) in Han Wistar rats.International Journal of Toxicology 19: abstracts page 25 (2000).

9. Natvig BC, Qualls CW and Allen JS. Toxicity of Hanatoxin GW279665A administered intravenously to CD-1 mice at 100 and 1000 ng/kg. International Journal of Toxicology 19: abstracts pages 25-26 (2000).

10. Torrey CE, Allen JS, Selinger K, Mann P, Miller RT and Rickert DE. Testing of clofibrate in a 26-week gavage study using p53+/- mice. International Journal of Toxicology 19: abstracts page 35 (2000).

11. Allen, JS, Hoivik DJ, Nold J and Wall HG. A single oral dose of N-methyl-N-nitrosourea (MNU) produces carcinogenicity within 13 weeks in male and female p53+/- mice. International Journal of Toxicology 19: abstracts page 36 (2000).

12. Melich DH, Owen K, Lightfoot RM, Selway SA and Allen JS. Toxicology of Pluronic F-68: A 14-day intravenous toxicity study in Han Wistar Rats. Toxicological Sciences 48(1-S): 325 (1999).

13. Allen JS. International Harmonization of Genetic Toxicology Guidelines under ICH Sponsorship: Toxicological Testing of Pharmaceuticals. Newsletter of the Carcinogenesis Specialty Section of the Society of Toxicology (February, 1996).

14. Allen JS, Chism J, Fennell S, and Washer G. Preclinical toxicology and pharmacokinetics of amylin antagonist peptide. Fundamental and Applied Toxicology 15: 181 (1995).

15. Ciofalo VB, Auletta CS and Allen JS. Acute intravenous pharmacology and toxicity of vasoactive intestinal polypeptide in the rat, mouse and dog. Fundamental and Applied Toxicology 15: 181 (1995).

16. Fowlie AJ, Darrington RT, Ostrout M, Bienvenu JG and Allen JS. Irritancy of acetate and succinate buffers during subcutaneous infusion in rats. Fundamental and Applied Toxicology 15: 73 (1995).

17. Campbell JA and Allen JS. Evaluation of peptide synthesis and purification reagents in the Salmonella typhimurium (Ames) test. Fundamental and Applied Toxicology 15: 7-8 (1995).

18. Kwanyuen P, Wilson JD, Williamson J, Campbell JA, Cariello NF and Allen JS. Micronucleus induction in bone marrow polychromatic erythrocytes of Han Wistar and Wu Wistar rats by cyclophosphamide, 5-fluorouracil and ethylmethanesulfonate. Environmental and Molecular Mutagenesis 25(S25): 29 (1995).

19. Williamson J, Wilson JD, Kwanyuen P, Campbell JA, Cariello NF, Allen JS and Parry JM. Micronucleus induction in bone marrow and peripheral blood erythrocytes by vinblastine sulfate: Threshold activity or linear response? Environmental and Molecular Mutagenesis 25(S25): 57 (1995)

20. Kwanyuen P, Guest RD, Walch KA, Campbell JA and Allen JS. Comparative studies on the induction of micronuclei in bone marrow polychromatic erythrocytes between Wistar HsdCpbi Wu and Sprague Dawley rats after oral administration of cyclophosphamide, 5-fluorouracil and ethylmethanesulfonate. Environmental and Molecular Mutagenesis 23(S23): 36 (1994).

21. Campbell JA, Allen JS, Perkins DG, San RHC, Bigger CA, Kumaru PV, Xu J, and Pant KJ. Evaluation of amiloride in the Ames Salmonella/reverse mutation assay, L5178Y tk+/- mouse lymphoma assay, micronucleus assay, CHO chromosome aberration assay, and the unscheduled DNA synthesis assay. Environmental and Molecular Mutagenesis 23(S23): 7 (1994).

22. Campbell JA, Allen JS. Mutagenicity of disperse dyes in Ames Salmonella typhimurium/mammalian microsome reverse mutation assay. Environmental and Molecular Mutagenesis 23(S23): 7 (1994).

23. Wink DA, Kasprzak KS, Maragos CM, Elespuru RK, Misra M, Dunams TM, Cebula TA, Koch WH, Andrews AW, Allen JS and Keefer LA. DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science 254: 1001-1003 (1991).

24. Claxton LD, Allen JS, Auletta A, Mortelmans K, Nestmann E and Zeiger E. Guide for the Salmonella typhimurium/mammalian microsome (Ames) test. In: American Society for Testing and Materials: Standards and Guides. Philadelphia, PA (1990).

 


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